雑誌のスタック

業績一覧

2022年

Teh-Wei Wang, Yoshikazu Johmura(corresponding authors), Narumi Suzuki, Satotaka Omori, Toshiro Migita, Kiyoshi Yamaguchi, Seira Hatakeyama, Satoshi Yamazaki, Eigo Shimizu, Seiya Imoto, Yoichi Furukawa, Akihiko Yoshimura and Makoto Nakanishi(corresponding authors)

Nature  02 Nov 2022  doi: 10.1038/s41586-022-05388-4

Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung

Nabora S. Reyes, Maria Krasilnikov, Nancy C. Allen, Jin Young Lee, Ben Hyams, Minqi Zhou, Supriya Ravishankar, Monica Cassandras, Chaoqun Wang, Imran Khan, Peri Matatia, Yoshikazu Johmura, Ari Molofsky, Michael Matthay, Makoto Nakanishi, Dean Sheppard, Judith Campisi and Tien Peng

Science 378, 192–201  13 Oct 2022  doi: 10.1126/science.abf3326

Alteration of Trop-2 expression in breast cancer cells by clinically used therapeutic agents and acquired tamoxifen resistance 

Jing ZhuWenwen WuYukiko TogashiNaoe Taira NihiraYoshikazu JohmuraDajiang Zhu, Makoto NakanishiYasuo Miyoshi, Tomohiko Ohta

Breast Cancer  27 Jul 2022  doi: 10.1007/s12282-022-01389-3. Online ahead of print.

Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice

Yasuhiro Nakano, Sachie Nakao, Minako Sueoka, Daigo Kasahara, Yuri Tanno, Hideaki Sumiyoshi, Tohru Itoh, Atsushi Miyajima, Katsuto Hozumi and Yutaka Inagaki 

Communications Biology  2022 January 21. doi: 10.1038/s42003-022-

2021年

TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis.

Suzuki N, Johmura Y (Co-corresponding authors), Wang TW, Migita T, Wu W, Noguchi R, Yamaguchi K, Furukawa Y, Nakamura S, Miyoshi I, Yoshimori T, Ohta T (Co-corresponding authors), Nakanishi M (Co-corresponding authors)

Autophagy

Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders.

Johmura Y (Co-corresponding authors), Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M (Co-corresponding authors)

Science 371, 265-270

A 3D tissue model-on-a-chip for studying the effects of human senescent fibroblasts on blood vessels.

Pauty J, Nakano S, Usuba R, Nakajima T, Johmura Y, Omori S, Sakamoto N, Kikuchi A, Nakanishi M, Matsunaga YT.

Biomaterials Science 9, 199-211

CCR2- and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis.

Zoshima T, Baba T, Tanabe Y, Ishida Y, Nakatani K, Nagata M, Mukaida N, Kawano M.

Rheumatology Online ahead of print

Crucial contribution of GPR56/ADGRG1, expressed by breast cancer cells, to bone metastasis formation.

Sasaki SI, Zhang D, Iwabuchi S, Tanabe Y, Hashimoto S, Yamauchi A, Hayashi K, Tsuchiya H, Hayakawa Y, Baba T, Mukaida N.

Cancer Sci 112, 4883-4893

Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway.

Baba T, Yoshida T, Tanabe Y, Nishimura T, Morishita S, Gotoh N, Hirao A, Hanayama R, Mukaida N.

Cell Death Dis 12, 322

Cancer non-stem cells as a potent regulator of tumor microenvironment: a lesson from chronic myeloid leukemia.

Mukaida N, Tanabe Y, Baba T.

Mol Biomed 2, 7

Rev

2020年

Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16 high Cells In Vivo.

Omori S, Wang TW, Johmura Y (corresponding authors), Kanai T, Nakano Y, Kido T, Susaki EA, Nakajima T, Shichino S, Ueha S, Ozawa M, Yokote K, Kumamoto S, Nishiyama A, Sakamoto T, Yamaguchi K, Hatakeyama S, Shimizu E, Katayama K, Yamada Y, Yamazaki S, Iwasaki K, Miyoshi C, Funato H, Yanagisawa M, Ueno H, Imoto S, Furukawa Y, Yoshida N, Matsushima K, Ueda HR, Miyajima A, Nakanishi M (corresponding authors).

 Cell Metabolism 32, 814-828

Two mouse models carrying truncating mutations in Magel2 show distinct phenotypes.

Ieda D, Negishi Y, Miyamoto T, Johmura Y, Kumamoto N, Kato K, Miyoshi I, Nakanishi M, Ugawa S, Oishi H, Saitoh S.

PLoS One 15, pone.0237814

FBXO22, an epigenetic multiplayer coordinating senescence, hormone signaling, and metastasis.

Johmura Y, Harris AS, Ohta T, and Nakanishi M.

Cancer Science 111, 2718-2725

Rev

Expansion of senescent megakaryocyte-lineage cells maintains CML cell leukemogenesis.

Tanabe Y, Kawamoto S, Takaku T, Morishita S, Hirao A, Komatsu N, Hara E, Mukaida N, Baba T.

 Blood Adv 4, 6175-6188

 Involvement of a Transcription factor, Nfe2, in Breast Cancer Metastasis to Bone.

Zhang D, Iwabuchi S, Baba T, Hashimoto SI, Mukaida N, Sasaki SI.

Cancers 12, 3003

Two-Faced Roles of Tumor-Associated Neutrophils in Cancer Development and Progression.

Mukaida N, Sasaki SI, Baba T.

Int J Mol Sci. 21, 3457

Rev

CCL4 Signaling in the Tumor Microenvironment.

Mukaida N, Sasaki SI, Baba T.

Adv Exp Med Biol 1231, 23-32

Rev

2019年

Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase.

Nishimura K (equally first contributed), Johmura Y (equally first contributed), Deguchi K, Jiang Z, Uchida KSK, Suzuki N, Shimada M, Chiba Y, Hirota T, Yoshimura SH, Kono K, Nakanishi M.

Nat communications 10, s41467-019-08957-w

Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.

Nakanishi K, Niida H, Tabata H, Ito T, Hori Y, Hattori M, Johmura Y, Yamada C, Ueda T, Takeuchi K, Yamada K, Nagata KI, Wakamatsu N, Kishi M, Pan YA, Ugawa S, Shimada S, Sanes JR, Higashi Y, Nakanishi M.

Cereb Cortex. 29, 3738-3751

A Deactivation Factor of Fibrogenic Hepatic Stellate Cells Induces Regression of Liver Fibrosis in Mice.

Yasuhiro Nakano, Akihide Kamiya, Hideaki Sumiyoshi, Kota Tsuruya, Tatehiro Kagawa, Yutaka Inagaki

Hepatology 24 September 2019  doi: 10.1002/hep.30965

2018年

Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.

Johmura Y, Maeda I, Suzuki N, Wu W, Goda A, Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T, Akiyama F, Maruyama R, Inoue JI, Furukawa Y, Ohta T, Nakanishi M.

Journal Clinical Investigation 128, 5603-19

Involvement of Prokineticin 2-expressing Neutrophil Infiltration in 5-Fluorouracil-induced Aggravation of Breast Cancer Metastasis to Lung.

Sasaki S, Baba T, Muranaka H, Tanabe Y, Takahashi C, Matsugo S, Mukaida N.

Mol Cancer Ther 17, 1515-1525

lveolar Macrophages Drive Hepatocellular Carcinoma Lung Metastasis by Generating Leukotriene B4.

Nosaka T, Baba T, Tanabe Y, Sasaki S, Nishimura T, Imamura Y, Yurino H, Hashimoto S, Arita M, Nakamoto Y, Mukaida N.

J Immunol 200, 1839-1852

Lung Macrophages: Multifunctional Regulator Cells for Metastatic Cells.

Mukaida N, Nosaka T, Nakamoto Y, Baba T.

Int J Mol Sci 20, 116

Rev

2017年

The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy.

Iwata T, Uchino T, Koyama A, Johmura Y, Koyama K, Saito T, Ishiguro S, Arikawa T, Komatsu S, Miyachi M, Sano T, Nakanishi M, Shimada M.

PLoS One 12, pone.0178221

Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation.

Yamaguchi L, Nishiyama A, Misaki T, Johmura Y, Ueda J, Arita K, Nagao K, Obuse C, Nakanishi M.

Scientific Reports 7, s41598-017-00136-5

A combination of genetic and biochemical analyses for the diagnosis of PI3K-AKT-mTOR pathway-associated megalencephaly.

Negishi Y, Miya F, Hattori A, Johmura Y, Nakagawa M, Ando N, Hori I, Togawa T, Aoyama K, Ohashi K, Fukumura S, Mizuno S, Umemura A, Kishimoto Y, Okamoto N, Kato M, Tsunoda T, Yamasaki M, Kanemura Y, Kosaki K, Nakanishi M, Saitoh S.

BMC Medical Genetics 18, s12881-016-0363-6

Chemokines as a Conductor of Bone Marrow Microenvironment in Chronic Myeloid Leukemia.

Mukaida N, Tanabe Y, Baba T.

Int J Mol Sci 18, 1824

Rev

Identification of a novel alpha-fetoprotein-expressing cell population induced by the Jagged1/Notch2 signal in murine fibrotic liver

Yasuhiro Nakano, Sachie Nakao, Hideaki Sumiyoshi, Kenichiro Mikami, Yuri Tanno, Minako Sueoka, Daigo Kasahara, Hiroshi Kimura, Tadashi Moro, Akihide Kamiya, Katsuto Hozumi, Yutaka Inagaki

Hepatology Communications 27 March 2017  doi:  10.1002/hep4.1026

2016年

HP1 regulates the localization of FANCJ at sites of DNA double-strand breaks.

Wu W, Togashi Y, Johmura Y, Miyoshi Y, Nobuoka S, Nakanishi M, Ohta T.

Cancer Science 107, 1406-1415

Defective DNA repair increases susceptibility to senescence through extension of Chk1-mediated G2 checkpoint activation.

Johmura Y, Yamashita E, Shimada M, Nakanishi, K., and Nakanishi M.

Scientific Reports 6, srep31194

Essential role of auto-activation circuitry on Aurora B-mediated H2AX-pS121 in mitosis.

Shimada M, Goshima T, Matsuo H, Johmura Y, Murata K, Tanaka H, Ikawa M,  Nakanishi K, and Nakanishi M.

Nature Communications 8, ncomms12059

SCFfbxo22-KDM4A targets methylated p53 for degradation and regulates senescence.

Johmura Y, Sun J, Kitagawa K, Nakanishi K, Kuno T, Naiki-Ito A, Sawada Y,  Miyamoto Y, Okabe A, Aburatani H, Li S, Miyoshi I, Takahashi S, Kitagawa M, and Nakanishi M.

Nature Communications 7, ncomms10574

 Loss of maintenance DNA methylation results in abnormal DNA origin firing during DNA replication.

Haruta M, Shimada M, Nishiyama A, Johmura Y, Tellec BL, Debatisse M, Nakanishi M

Biochemical and Biophysical Research Communications 469, 960-966

Multiple facets of p53 in senescence induction and maintenance.

Johmura Y and Nakanishi M.

Cancer Science 107, 1550-1555

Rev

Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancerassociated fibroblast accumulation.

Tanabe Y, Sasaki S, Mukaida N, Baba T.

Oncotarget 7, 48335-48345

Gemcitabine induces cell senescence in human pancreatic cancer cell lines.

Song Y, Baba T, Mukaida N.

Biochem Biophys Res Commun 477, 515-519

MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice.

Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N.

Blood 127, 2607-2617

Essential roles of the interaction between cancer cell-derived chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast cancer bone metastasis.

Sasaki S, Baba T, Nishimura T, Hayakawa Y, Hashimoto SI, Gotoh N, Mukaida N.

Cancer Lett 378, 23-32

Chemokines in chronic myeloid leukemia.

Mukaida N, Baba T.

Rinsho Ketsueki 57, 129-136

Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice

Sota Kodama, Yasuhiro Nakano(Co-first author), Koji Hirata1, Kenichiro Furuyama, Masashi Horiguchi, Takeshi Kuhara, Toshihiko Masui, Michiya Kawaguchi, MaureenGannon, ChristopherV. E.Wright, Shinji Uemoto and Yoshiya Kawaguchi

Scientific Reports  18 February 2016  doi: 10.1038/srep21211

2015年

High-dose cyclophosphamide induces specific tumor immunity with concomitant recruitment of LAMP1/CD107a-expressing CD4-positive T cells into tumor sites.

Naito T, Baba T, Takeda K, Sasaki S, Nakamoto Y, Mukaida N.

Cancer lett 366, 93-99

Gemcitabine-induced CXCL8 expression counteracts its actions by inducing tumor neovascularization.

Song Y, Baba T, Li YY, Furukawa K, Tanabe Y, Matsugo S, Sasaki S, Mukaida N.

Biochem Biophys Res Commun 458, 341-346

Establishment of a vascular endothelial cell-reactive type II NKT cell clone from a rat model of autoimmune vasculitis.

Iinuma C, Waki M, Kawakami A, Yamaguchi M, Tomaru U, Sasaki N, Masuda S, Matsui Y, Iwasaki S, Baba T, Kasahara M, Yoshiki T, Paletta D, Herrmann T, Ishizu A.

Int Immunol 27, 105-114

Disappearance of centroacinar cells in the Notch ligand-deficient pancreas

Yasuhiro Nakano, Naoko Negishi, Seiho Gocho, Tetsuya Mine, Yuri Sakurai, Masaki Yazawa, Koichiro Abe, Hideo Yagita, Sonoko Habu, Ryoichiro Kageyama, Yoshiya Kawaguchi, Katsuto Hozumi

Genes to Cells  27 April 2015  doi: 10.1111/gtc.12243

2014年

Necessary and Sufficient role for a mitosis skip in senescence induction.

Johmura Y, Shimada M, Misaki T, Naiki-Ito A, Miyoshi H, Motoyama N, Ohtani N, Hara E, Nakamura M, Morita A, Takahashi S, and Nakanishi M.

Molecular Cell 55, 73-84

CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint.

Hirokawa T, Shiotani B, Shimada M, Murata K, Johmura Y, Haruta M, Tahara H,  Takeyama H, and Nakanishi M.

Cancer Research 74, 3880-3889

Mammal-specific H2A variant, H2ABbd, is involved in apoptotic induction via activation of NF-kappaB signaling pathway.

Goshima T, Shimada M, Sharif J, Matsuo H, Misaki T, Johmura Y, Murata K, Koseki H,  and Nakanishi M.

Journal of Biological Chemistry, 289, 11656-116669

Crucial involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice.

Sasaki S, Baba T, Shinagawa K, Matsushima K, Mukaida N.

Int J Cancer 135, 1297-1306

Ag and IL-2 immune complexes efficiently expand Ag-specific Treg cells that migrate in response to chemokines and reduce localized immune responses.

Hamano R, Baba T, Sasaki S, Tomaru U, Ishizu A, Kawano M, Yamagishi M, Mukaida N.

Eur J Immunol 44, 1005-1015

Role of macrophage inflammatory protein (MIP)-1α/CCL3 in leukemogenesis.

Baba T, Mukaida N.

Mol Cell Oncol 1, e29899

Rev

2013年

Chemokines in cancer development and progression and their potential as targeting molecules for cancer treatment.

Mukaida N, Sasaki S, Baba T.

Mediators Inflamm 2014, 170381

Rev

UHRF1-dependent H3K23 ubiquitylation couples DNA methylation and replication.

Nishiyama A, Yamaguchi L, Sharif J, Johmura Y, Kawamura T, Nakanishi K,  Shimamura K, Arita K, Kodama T, Ishikawa F, Koseki H, and Nakanishi M.

Nature, 502, 249-253

Increased rotein stability of CDKN1c causes a gain-of-function Phenotype in paients with IMAGe syndrome.

Hamajima N, Johmura Y, Suzuki S, Nakanishi M, and Saito S.

PLoS One 8, pone.0075137

MIP-1alpha/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia.

Baba T, Naka K, Morishita S, Komatsu N, Hirao A, Mukaida N.

J Exp Med 210, 2661-2673

Possible implication of Fc γ receptor-mediated trogocytosis in susceptibility to systemic autoimmune disease.

Masuda S, Iwasaki S, Tomaru U, Baba T, Katsumata K, Ishizu A.

Clin Dev Immunol 2013, 345745

Rev

2012年

Identification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathway.

Lee KH, Johmura Y, Yu LR, Park JE, Gao Y, Bang JK, Zhou M, Veenstra TD, Kim BY, Erikson RL, and Lee KS.

EMBO Journal 31, 3104-3117

Critical role of TNF-α-induced macrophage VEGF and iNOS production in the experimental corneal neovascularization.

Lu P, Li L, Liu G, Baba T, Ishida Y, Nosaka M, Kondo T, Zhang X, Mukaida N.

Invest Ophthalmol Vis Sci 53, 3516-3526

Decreased proteasomal activity causes age-related phenotypes and promotes the development of metabolic abnormalities.

Tomaru U, Takahashi S, Ishizu A, Miyatake Y, Gohda A, Suzuki S, Ono A, Ohara J, Baba T, Murata S, Tanaka K, Kasahara M.

Am J Pathol 180, 963-972

 Identification of a phenanthrene derivative as a potent anticancer drug with Pim kinase inhibitory activity.

Wang YY, Taniguchi T, Baba T, Li YY, Ishibashi H, Mukaida N.

Cancer Sci 103, 107- 115

Mechanism of Fcγ receptor-mediated trogocytosis-based false-positive results in flow cytometry.

Masuda S, Iwasaki S, Tomaru U, Sato J, Kawakami A, Ichijo K, Sogo S, Baba T, Katsumata K, Kasahara M, Ishizu A.

PLoS One 7, e52918

Decrease of peripheral and intestinal NKG2A-positive T cells in patients with ulcerative colitis.

Katsurada T, Kobayashi W, Tomaru U, Baba T, Furukawa S, Ishizu A, Takeda K, Sakamoto N, Asaka M, Takeda H, Kasahara M.

PLoS one 7, e44113

Novel process of intrathymic tumor-immune tolerance through CCR2-mediated recruitment of Sirpalpha+ dendritic cells: a murine model.

Baba T, Badr Mel S, Tomaru U, Ishizu A, Mukaida N.

PloS one 7, e41154

Chemokines in tumor development and progression.

Mukaida N, Baba T.

Exp Cell Res 318, 95-102

Rev

Regulation of Microtubule-based Microtubule Nucleation by Mammalian Polo-like kinase.

Johmura Y, Soung NK, Park JE, Yu LR, Zhou M, Bang JK, Kim BY, Veenstra TD,  Erikson RL, and Lee KS.

Poceedings of the National Academy of Sciences of the United States of America 108, 11446-11451

2011年

Ablation of the Ccr2 gene exacerbates polyarthritis in interleukin-1 receptor antagonist-deficient mice.

Fujii H, Baba T, Ishida Y, Kondo T, Yamagishi M, Kawano M, Mukaida N.

Arthritis Rheum 63, 96-106

Plasma-dependent, antibody- and Fcγ receptor-mediated translocation of CD8 molecules from T cells to monocytes.

Iwasaki S, Masuda S, Baba T, Tomaru U, Katsumata K, Kasahara M, Ishizu A.

Cytometry A 79, 46-56

2010年

Polo-box domain: a versatile mediator of polo-like kinase function.

Park JE, Soung NK, Johmura Y, Kang YH, Liao C, Lee KH, Park CH, Nicklaus MC, and Lee KS.

Cellular and Molecular Life Sciences 67, 1957-1970

Rev

Antitumor effect after radiofrequency ablation of murine hepatoma is augmented by an active variant of CC Chemokine ligand 3/macrophage inflammatory protein-1alpha.

Iida N, Nakamoto Y, Baba T, Nakagawa H, Mizukoshi E, Naito M, Mukaida N, Kaneko S.

Cancer Res 70, 6556-6565

Identification of stemonamide synthetic intermediates as a novel potent anticancer drug with an apoptosis-inducing ability.

 Li YY, Wang YY, Taniguchi T, Kawakami T, Baba T, Ishibashi H, Mukaida N.

 Int J Cancer 127, 474-484

Crucial involvement of the CX3CR1-CX3CL1 axis in dextran sulfate sodium-mediated acute colitis in mice.

Kostadinova FI, Baba T, Ishida Y, Kondo T, Popivanova BK, Mukaida N.

J Leukoc Biol 88, 133-143

Cyclic AMP response element-binding protein is implicated in IL-6 production from arthritic synovial cells

Ishizu A, Abe A, Miyatake Y, Baba T, Iinuma C, Tomaru U, Yoshiki T.

Mod Rheumatol 20, 134-138

2009年

Fad24 Causes Hyperplasia in Adipose Tissue and Improves Glucose Metabolism.

Johmura Y, Watanabe K, Kishimoto K, Ueda T, Shimada S, Osada S, Nishizuka M, and Imagawa M.

Biological and Pharmaceutical Bulletin 32, 1656-1664

Crucial contribution of thymic Sirp alpha+ conventional dendritic cells to central tolerance against blood-borne antigens in a CCR2-dependent manner.

Baba T, Nakamoto Y, Mukaida N.

J Immunol 183, 3053-3063

Exclusive expression of proteasome subunit {beta}5t in the human thymic cortex.

Tomaru U, Ishizu A, Murata S, Miyatake Y, Suzuki S, Takahashi S, Kazamaki T, Ohara J, Baba T, Iwasaki S, Fugo K, Otsuka N, Tanaka K, Kasahara M.

Blood 113, 5186-5191

Essential contribution of Ets-1 to constitutive Pim-3 expression in human pancreatic cancer cells.

Li YY, Wu Y, Tsuneyama K, Baba T, Mukaida N.

Cancer Sci 100, 396-404

2008年

FAD24, a regulator of adipogenesis and DNA replication, inhibits H-RAS-mediated transformation by repressing NF-kappaB activity.

Johmura Y, Suzuki M, Osada S, Nishizuka M, and Imagawa M.

Biochemical and Biophysical Research Communications 369, 464-47

FAD24 acts in concert with histone acetyltransferase HBO1 to promote adipogenesis by controlling DNA replication.

Johmura Y, Osada S, Nishizuka M, and Imagawa M.

Journal of Biological Chemistry 283, 2265-2274

FAD24, a regulator of adipogenesis, is required for the regulation of DNA replication in cell proliferation.

Johmura Y, Osada S, Nishizuka M, and Imagawa M.

Biological and Pharmaceutical Bulletin 31, 1092-1095

CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process.

Wu Y, Li YY, Matsushima K, Baba T, Mukaida N.

J Immunol 181, 6384-6393

Tumor cell apoptosis induces tumor-specific immunity in a CC chemokine receptor 1- and 5-dependent manner in mice.

Iida N, Nakamoto Y, Baba T, Kakinoki K, Li YY, Wu Y, Matsushima K, Kaneko S, Mukaida N.

J Leukoc Biol 84, 1001-1010

Protective roles of the fractalkine/CX3CL1-CX3CR1 interactions in alkali-induced corneal neovascularization through enhanced antiangiogenic factor expression.

Lu P, Li L, Kuno K, Wu Y, Baba T, Li YY, Zhang X, Mukaida N.

J Immunol 180, 4283-4291

Rat CD4+CD8+ macrophages kill tumor cells through an NKG2D- and granzyme/perforin-dependent mechanism.

Baba T, Iwasaki S, Maruoka T, Suzuki A, Tomaru U, Ikeda H, Yoshiki T, Kasahara M, Ishizu A.

J Immunol 180, 2999-3006

2007年

Characterization of novel genes regulating adipocyte differentiation.

Johmura Y (Corresponding authors)

Yakugaku Zasshi 127, 135-142

Rev

2006年

MHC class I-like MILL molecules are beta2-microglobulin-associated, GPI-anchored glycoproteins that do not require TAP for cell surface expression.

Kajikawa M, Baba T, Tomaru U, Watanabe Y, Koganei S, Tsuji-Kawahara S, Matsumoto N, Yamamoto K, Miyazawa M, Maenaka K, Ishizu A, Kasahara M.

J Immunol 177, 3108-3115

Role of neuronal interferon-gamma in the development of myelopathy in rats infected with human T-cell leukemia virus type 1.

Miyatake Y, Ikeda H, Ishizu A, Baba T, Ichihashi T, Suzuki A, Tomaru U, Kasahara M, Yoshiki T.

Am J Pathol 169, 189-199

CD4+/CD8+ macrophages infiltrating at inflammatory sites: a population of monocytes/macrophages with a cytotoxic phenotype.

Baba T, Ishizu A, Iwasaki S, Suzuki A, Tomaru U, Ikeda H, Yoshiki T, Kasahara M.

Blood 107, 2004-2012

2005年

SLC39A14, a LZT protein, is induced in adipogenesis and transports zinc.

Tominaga K, Kagata T, Johmura Y, Nishizuka M, and Imagawa M.

FEBS Journal 272, 1590-1599

Malignant transformation of thymoma in recipient rats by heterotopic thymus transplantation from HTLV-I transgenic rats.

Tsuji T, Ikeda H, Tsuchikawa T, Kikuchi K, Baba T, Ishizu A, Yoshiki T.

Lab Invest 85, 851-861

Chronic graft-versus-host disease-like autoimmune disorders spontaneously occurred in rats with neonatal thymus atrophy.

Baba T, Ishizu A, Ikeda H, Miyatake Y, Tsuji T, Suzuki A, Tomaru U, Yoshiki T.

Eur J Immunol 35, 1731-1740

Aberrant gene expression by CD25+CD4+ immunoregulatory T cells in autoimmune-prone rats carrying the human T cell leukemia virus type-I gene.

Hayase H, Ishizu A, Ikeda H, Miyatake Y, Baba T, Higuchi M, Abe A, Tomaru U, Yoshiki T.

Int Immunol 17, 677-684

The role of IFN-gamma in cattle infected with Theirelia sergenti.

Hagiwara K, Tokuda M, Baba T, Yamanaka H, Kirisawa R, Tsuji M, Ishihara C, Iwai H.

Vet Parasitol 127, 105-110.

2004年

Fad24, a mammalian homolog Noc3p, is a positive regulator in adipocyte differentiation. 

Tominaga K, Johmura Y, Nishizuka M, and Imagawa M.

Journal of Cell Science 17, 6217-6226

The novel gene fad104, containing a fibronectin type III domain, has a significant role in adipogenesis.

Tominaga K, Kondo C, Johmura Y, Nishizuka M, and Imagawa M.

FEBS Letters 577, 49-54

Hematopoietic progenitor cells as possible origins of epithelial thymoma in a human T lymphocyte virus type I pX gene transgenic rat model.

Tsuchikawa T, Ikeda H, Kikuchi K, Tsuji T, Baba T, Ishizu A, Tanaka Y, Kato H, Yoshiki T.

Lab Invest 84, 245-252